PV-0311 MRI-based tumour control probability model in particle therapy
نویسندگان
چکیده
منابع مشابه
Tumour Therapy with Particle Beams
Photons are exponentially attenuated in matter producing high doses close to the surface. Therefore they are not well suited for the treatment of deep seated tumours. Charged particles, in contrast, exhibit a sharp increase of ionisation density close to the end of their range, the so-called Bragg-peak. The depth of the Bragg-peak can be adjusted by varying the particle’s energy. In parallel wi...
متن کاملTumour Control Probability in Cancer Stem Cells Hypothesis
The tumour control probability (TCP) is a formalism derived to compare various treatment regimens of radiation therapy, defined as the probability that given a prescribed dose of radiation, a tumour has been eradicated or controlled. In the traditional view of cancer, all cells share the ability to divide without limit and thus have the potential to generate a malignant tumour. However, an emer...
متن کاملAre more complicated tumour control probability models better?
Mathematical models for the tumour control probability (TCP) are used to estimate the expected success of radiation treatment protocols of cancer. There are several TCP models in the literature, from the simplest (Poissonian TCP) to the well-advanced stochastic birth-death processes. Simple and complex models often make the same predictions. Hence, here, we present a systematic study where we c...
متن کاملDerivation of the tumour control probability (TCP) from a cell cycle model
In this paper, a model for the radiation treatment of cancer which includes the effects of the cell cycle is derived from first principles. A malignant cell population is divided into two compartments based on radiation sensitivities. The active compartment includes the four phases of the cell cycle, while the quiescent compartment consists of the G0 state. Analysis of this active-quiescent rad...
متن کاملmortality forecasting based on lee-carter model
over the past decades a number of approaches have been applied for forecasting mortality. in 1992, a new method for long-run forecast of the level and age pattern of mortality was published by lee and carter. this method was welcomed by many authors so it was extended through a wider class of generalized, parametric and nonlinear model. this model represents one of the most influential recent d...
15 صفحه اولذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Radiotherapy and Oncology
سال: 2019
ISSN: 0167-8140
DOI: 10.1016/s0167-8140(19)30731-5